|
KMID : 0389420080160030207
|
|
Korean Journal of Stress Research
2008 Volume.16 No. 3 p.207 ~ p.211
|
|
|
Difference in Plasma Insulin-like Growth Factor-1 Concentration according to Degree of Stress
|
|
Kong Mi-Hee
Kim Bom-Taeck
Park Sat-Byul
Joo Nam-Seok
Kim Kwang-Min
|
|
|
Abstract
|
|
|
Purpose: Stress by activation the hypothalamic-pituiraty-adrenal axis causes the release cortisol. Increased cortisol secretion is associated with low levels of growth hormone concentrations. Insulin-like growth factor-1 (IGF-1) production is stimulated by growth hormone. We hypothesize that stress may be associated with IGF-1 levels.
Methods: We assessed circulating levels of IGF-1 in 2,371 individuals (Men 1,460, Women 911) who coming at health promotion center. Stress score was measure by Modified-Korean BEPSI self reported questionnaire.
Results: In young men, IGF-1 level of high stress group was significantly decreased than lower stress group. This significance was remained after multivariable adjusted. But, young women and elderly groups had not significant difference of IGF-1 level according to the low stress or high stress.
Conclusion: The IGF-1 level of high stress group was decreased than low stress group. But, this significant difference was showed in only young men.
|
|
|
KEYWORD
|
|
|
Stress, Modified-Korean BEPSI, Insulin-like growth factor-1
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|